Hōʻike ʻia ʻo Curcumin i mea e hoʻomaikaʻi ai i nā Marker Inflammatory Markum

Nā hualoaʻa o kahi noi hou i paʻi ʻia i loko o ka puke pai ʻO Biomed Central BMC i hōʻike ʻia he like ka hopena o ka turmeric extract me ka paracetamol i ka hoʻēmi ʻana i ka ʻeha a me nā ʻōuli ʻē aʻe o ka osteoarthritis kuli (OA). Ua hōʻike ʻia ke aʻo ʻana ua ʻoi aku ka maikaʻi o ka hui bioavailable i ka hōʻemi ʻana i ka mumū.

ʻO ka Osteoarthritis kahi maʻi hoʻohaʻahaʻa o nā hono articular i hoʻohālikelike ʻia e ka haki ʻana o ka cartilage, ka hui ʻana, nā ligament, a me ka iwi ma lalo. ʻO nā hiʻohiʻona maʻamau o ka osteoarthritis ka paʻakikī a me ka ʻeha.

Ua alakaʻi ʻia e Shuba Singhal, PhD, ua alakaʻi ʻia kēia noiʻi loiloi kaulike ʻia ma ke Keʻena ʻo Orthopedics o Lok Nayak Jai Prakash Hospital / Maulana Azad Medical College, New Delhi. No ke aʻo ʻana, 193 mau maʻi i ʻike ʻia me ka osteoarthritis o ke kuli i randomized e loaʻa ai kekahi turmeric extract (BCM-95) ma ke ʻano he 500 mg capsule ʻelua mau manawa i kēlā me kēia lā, a i ʻole he 650 mg papa o ka paracetamol ʻekolu manawa i kēlā me kēia lā no ʻeono pule.

Ua loiloi ʻia nā ʻōuli o ke kuli o ka ʻeha, ka paʻakikī paʻa, a me ka hoʻemi ʻia o ke kino i ka hoʻohana ʻana i ka Western Ontario a me McMaster Universities Osteoarthritis Index (WOMAC). Ma hope o ʻeono mau pule o ka hoʻomaʻamaʻa ʻana, hōʻike ka nānā ʻana i ka mea pane i ka hoʻomaikaʻi nui ʻana i nā helu WOMAC ma nā palena āpau i hoʻohālikelike ʻia me ka hui paracetamol, me 18% o ka hui BCM-95 e hōʻike nei i ka hoʻomaikaʻi hou he 50%, a me 3% o nā kumuhana e hōʻike nei i ka hoʻomaikaʻi ʻana he 70%.

Hōʻike maikaʻi ʻia kēia mau hopena i nā māka serum o ka hui BCM-95: ua hoʻemi ʻia nā pae CRP e 37,21%, a ua ʻoki ʻia nā pae TNF-α e 74.81%, e hōʻike ana ua hana ʻo BCM-95 ma mua o ka paracetamol.

ʻO ka noiʻi kahi mea i ukali ʻia i kahi aʻo ʻana ʻo Arjuna i mālama ʻia ma kahi o hoʻokahi makahiki i hala e hōʻike ana i kahi pilina maikaʻi ma waena o kāna hae curcumin formulate a me ka mālama osteoarthritic.

"ʻO ka pahuhopu o ke aʻo ʻana i kēia manawa ke kūkulu ʻana ma luna o nā noiʻi mua e hāʻawi i ka mōakāka maikaʻi a me ke kikoʻī ma o ka hoʻokomo ʻana i nā māka a me ke kiʻina helu ʻoi aku ka maikaʻi," i ʻōlelo ʻia ʻo Benny Antony, ka luna hoʻomalu hui no Arjuna. "ʻO ka hopena anti-arthritic o BCM-95 i ka osteoarthritis e pili ana i kona hiki ke hoʻololi i nā māka anti-inflammatory TNF a me CRP."

ʻO Knee OA ke kumu nui o ke kīnā a me ka ʻeha ma waena o nā poʻe mākua a me nā ʻelemakule. Kuhi ʻia he 10 a 15% o nā mākua a pau ma mua o 60 mau makahiki i kekahi kekelē o ka OA, me ka prevalence kiʻekiʻe ma waena o nā wahine ma mua o nā kāne.

"Hōʻoia kēia noi i ka hopena anti-arthritic o BCM-95 a hāʻawi i ka manaolana hou no nā miliona e hoʻomaikaʻi i ko lākou ola," i ʻōlelo ʻia ʻo Nipen Lavingia, kākāʻōlelo aʻoaʻo aʻoaʻo no Arjuna Natural i hoʻokumu ʻia ma Dallas, TX.

"Ke aʻo hou nei mākou e pili ana i nā hana ma hope o ka curcumin hopena anti-inflammatory a mākou e manaʻo nei he hopena ia o kona hiki ke kāohi i nā hōʻailona pro-inflammatory, e like me prostaglandins, leukotrienes, a me cyclooxygenase-2. Hoʻohui ʻia, ua hōʻike ʻia ka curcumin e kāohi i nā cytokine pro-inflammatory a me nā mea uwao o ko lākou hoʻokuʻu ʻia ʻana, e like me ka tumrosis factor-α (TNF-α), IL-1, IL-8, a me ka nitric oxide synthase, "i ʻōlelo ʻo Antony.

ʻO kā BCM-95 hui kuʻikuʻi o curcuminoids a me nā mea aila waiwai nui turmerone e lanakila i ka curcumin's bioavailability hurdles ma muli o kona ʻano lipophilic kiʻekiʻe.


Ka manawa o ka manawa: Apr-12-2021