ʻO nā hopena o kahi noiʻi hou i paʻi ʻia ma ka puke pai Biomed Central BMC ua hōʻike ʻia ka hopena turmeric e like me ka paracetamol i ka hōʻemi ʻana i ka ʻeha a me nā hōʻailona ʻē aʻe o ka osteoarthritis kuli (OA). Ua hōʻike ʻia ka haʻawina ʻoi aku ka maikaʻi o ka pūhui bioavailable i ka hōʻemi ʻana i ka mumū.
ʻO ka Osteoarthritis kahi maʻi degenerative o nā ami articular i hōʻike ʻia e ka haki ʻana o ka cartilage, ka ʻili hui, nā ligaments, a me ka iwi lalo. ʻO nā hōʻike maʻamau o ka osteoarthritis ka ʻoʻoleʻa a me ka ʻeha.
Ua alakaʻi ʻia e Shuba Singhal, PhD, ua mālama ʻia kēia haʻawina hoʻonaʻauao i hoʻopaʻa ʻia ma ke Keʻena ʻo Orthopedics o Lok Nayak Jai Prakash Hospital / Maulana Azad Medical College, New Delhi. No ka noiʻi ʻana, ua koho ʻia nā maʻi 193 i loaʻa i ka osteoarthritis o ke kuli e loaʻa i kahi ʻāpana turmeric (BCM-95) ma ke ʻano he 500 mg capsule ʻelua manawa i kēlā me kēia lā, a i ʻole he papa 650 mg o ka paracetamol ʻekolu manawa i kēlā me kēia lā no ʻeono pule.
Ua loiloi ʻia nā hōʻailona o ka ʻeha o nā kuli, ʻoʻoleʻa hui, a me ka emi ʻana o ka hana kino me ka Western Ontario a me McMaster Universities Osteoarthritis Index (WOMAC). Ma hope o ʻeono pule o ka hoʻomaʻamaʻa ʻana, ua hōʻike ka loiloi pane i ka hoʻomaikaʻi nui ʻana i nā helu WOMAC ma nā ʻāpana āpau e like me ka hui paracetamol, me 18% o ka hui BCM-95 e hōʻike ana i ka hoʻomaikaʻi 50%, a me 3% o nā kumuhana e ʻike ana i ka hoʻomaikaʻi 70%.
Ua hōʻike maikaʻi ʻia kēia mau hopena ma ka hui BCM-95 i ka serum inflammatory markers: Ua hoʻemi ʻia nā pae CRP e 37.21%, a ua ʻoki ʻia nā pae TNF-α e 74.81%, e hōʻike ana i ka hana ʻoi aku o ka BCM-95 ma mua o ka paracetamol.
ʻO ke aʻo ʻana he hahai ʻana i kahi haʻawina Arjuna i hana ʻia ma kahi makahiki i hala aku nei e hōʻike ana i kahi pilina maikaʻi ma waena o kāna hoʻokumu curcumin poʻokela a me ka mālama osteoarthritic.
"ʻO ka pahuhopu o ke aʻo ʻana i kēia manawa ʻo ia ke kūkulu ʻana ma luna o nā haʻawina mua e hāʻawi i ka ʻike a me ka kikoʻī ʻoi aku ka maikaʻi ma o ka hoʻokomo ʻana i nā māka hou aʻe a me ke ʻano hana helu ʻoi aku ka maikaʻi," wahi a Benny Antony, ka luna hoʻokele hui no Arjuna. "ʻO ka hopena anti-arthritic o BCM-95 i ka osteoarthritis e pili ana i kona hiki ke hoʻololi i nā hōʻailona anti-inflammatory TNF a me CRP."
ʻO Knee OA ke kumu nui o ke kīnā a me ka ʻeha ma waena o ka poʻe makua a me ka ʻelemakule. Ua manaʻo ʻia he 10 a 15% o nā pākeke a pau ma mua o 60 mau makahiki i loaʻa kekahi degere OA, me ka piʻi ʻana o ka maʻi ma waena o nā wahine ma mua o nā kāne.
"Ke hōʻoia hou nei kēia haʻawina i ka hopena anti-arthritic o BCM-95 a hāʻawi i ka manaʻolana hou no nā miliona e hoʻomaikaʻi i ko lākou maikaʻi o ke ola," wahi a Nipen Lavingia, ke kākā'ōlelo hou no Arjuna Natural i hoʻokumu ʻia ma Dallas, TX.
"Ke aʻo hou nei mākou e pili ana i nā hana ma hope o ka hopena anti-inflammatory o curcumin a mākou i manaʻo ai he hopena ia o kona hiki ke kāohi i nā hōʻailona pro-inflammatory, e like me prostaglandins, leukotrienes, a me cyclooxygenase-2. Eia kekahi, ua hōʻike ʻia ka curcumin e kāohi i nā cytokines pro-inflammatory a me nā mea hoʻolaha o kā lākou hoʻokuʻu ʻana, e like me ka tumor necrosis factor-α (TNF-α), IL-1, IL-8, a me ka nitric oxide synthase, "wahi a Antony.
ʻO ka hui pū ʻana o BCM-95 o nā curcuminoids a me nā ʻāpana aila waiwai nui i ka turmerone e lanakila i nā pilikia bioavailability hiʻohiʻona o curcumin ma muli o kona ʻano lipophilic kiʻekiʻe.
Ka manawa kau: Apr-12-2021